October 2025
Exhibition Design
VISTA Science Experience Center
5 min read
With: Lucy Li, Alan Schiegl

AI the Scientist

Developing an interactive exhibit exploring the future of AI in science.

What does AI mean for research?

Protein research has been quietly transformed. AI-tools like AlphaFold now predict molecular structures in hours that once took decades of painstaking lab work. But the science is abstract, the tools invisible, and the implications difficult to grasp. VISTA Science Experience Center commissioned us to make this shift legible to visitors.

Portrait of Max Perutz working in his laboratory
© Life Sciences Foundation
Higgs event during head-on collision of protons
Higgs event during head-on collision of protons

Embodying the Abstract

The central design challenge emerged immediately: how do you give physical form to artificial intelligence without falling into tired metaphors or sterile visualizations? We started our process by meeting the scientists themselves.

Hero composite showing the main installation

Meeting the Scientists

Our collaboration began with extensive interviews with researchers Alex Bronstein and Florian Praetorius, as well as visits to their groups' labs. These conversations revealed what a day in the life of a cutting-edge scientist truly looks like — how they actually use and develop these tools, where their work is misunderstood, and what fears and hopes surround it.

Portrait of Alex Bronstein in his laboratory
© ISTA
Portrait of Florian Praetorius discussing protein structures

Building on these insights, we developed wireframes in close collaboration with Alex and Florian. Early sketches were tested against the realities of their daily work, and refined through ongoing feedback rounds ensuring the design genuinely reflected how they think and work.


Interface Design Philosophy

The UI design needed to reflect the dual nature of protein research: both organic and computational. We developed a visual language that mirrors the colors of "amino acids" in our digital interfaces, creating an immediate connection between the molecular world and its digital representation.

Screen interface showing protein visualization
Amino acids and digital proteins
Interface displaying protein structures
Proteins

Engineering the Physical

From our first sketches, we knew the installation required something tangible. Something visitors could watch, follow, almost predict, and then lose. The marble tracks… a small engineered ecosystem. Each track, made from a readily available system, runs on custom-built active components. The code then creates a continuous dialogue between physical and digital, three tracks embodying three different approaches to scientific inquiry.

Behind-the-scenes view of marble track construction
Technical detail of marble track mechanisms


Before AI: Perutz and the Hand-Built Hemoglobin

Before artificial intelligence transformed molecular research, scientists like Max Perutz spent decades manually mapping protein structures. His work on hemoglobin required painstaking crystallographic analysis, building physical models atom by atom. This methodical, almost artisanal approach to understanding life's machinery provides essential context for appreciating AI's revolutionary impact.

Wide view of Max Perutz working in his laboratory with molecular models
© Life Sciences Foundation

Structural Transparency

Our interface displays the fundamental elements of protein structure: the chains that must be sorted stand for the constructive relationships between components. Every element is visible, traceable, understandable.

Full interface view showing protein chain visualization

The marble track mirrors this philosophy through complete transparency. Every movement is traceable, slow and deliberate, allowing visitors to follow each decision point and understand the underlying logic.


Enter Machine Learning

Machine learning fundamentally changes the scientific process. Systems like Rosetta and other computational tools shift research from careful, individual observations to massive parallel processing. The implications extend far beyond efficiency: they challenge our understanding of how discovery happens.

Interface showing marble track integration
Close-up of generate button interface

Generative Grids

Our interface reflects this transformation through generative grids that show iteration, multitude, and repetition while maintaining a sense of organization. The UI moves fast, processes large numbers, but always maintains visual coherence—mirroring how machine learning accelerates research while creating new forms of scientific understanding. The system demonstrates how AI doesn't just speed up existing processes—it creates entirely new ways of thinking about molecular relationships.

Interface showing generative grid patterns with scientific data
© Lucy Li

The marble tracks embody this acceleration through tunnels, self-folding paths, electric switches, and multiple simultaneous routes. The physical system becomes a metaphor for AI's ability to explore many possibilities simultaneously, folding in on itself like the proteins it designs.


Three Speculative Futures

What now? How will the future "unfold"? ;-) As speculative designers, we developed three distinct lenses through which visitors can explore potential futures. Each scenario presents different relationships between humans, AI, and scientific discovery, inviting contemplation rather than providing definitive answers.

Interface showing three future scenario options

1. AI as Scientist

In this future, artificial intelligence designs faster than any human, solving problems we no longer fully understand. Scientific progress accelerates, but its logic becomes hidden within machine processes. The fundamental question emerges: what happens when the answers become unreadable to human comprehension?

How do you stay curious when the answers are unreadable?

Interface showing AI scientist scenario
Interface showing AI scientist scenario

2. Symbiotic Collaboration

The symbiotic collaboration scenario imagines AI handling computational heavy lifting—fluid systems, ecosystems, entire networks of microbial life. But tools built by humans risk shaping the world in our image. The critical question becomes: can we build with nature, not over it?

Can we build with nature, not over it?

Interface showing symbiotic collaboration scenario

3. Biohacking Chaos

In the final scenario, AI tools become unlocked, remixed, and reshaped by anyone with open-source access. Innovation explodes, but so do the risks. The democratization of powerful biological design tools raises urgent questions about governance and responsibility. What do you grow in a world without rules?

What do you grow in a world without rules?

Interface showing biohacking chaos scenario

The interface presents this scenario with appropriate visuals, suggesting both the creative potential and inherent dangers of unrestricted access to AI-powered biological design.

Interface showing red protein
Interface showing potentially harmful design goals

The marble track system culminates in a literal cone—a funnel that represents the expanding possibilities and increasing uncertainty as we move further into AI-driven futures.


Our relationship with AI

The installation integrates all elements: context, contemporary science, speculative futures, and physical interaction, into a cohesive experience that invites both understanding and reflection.

AI is no magic, but a tool with profound implications. By grounding abstract concepts in physical interactions and historical context, we create lasting connections. Designed experiences like this foster genuine comprehension by engaging multiple forms of intelligence: visual, kinesthetic, emotional, and analytical. Visitors leave not just informed, but transformed in their relationship to both science and artificial intelligence.

Visitors engaging with the interactive installation
© Lucy Li

Credits

Commissioned by: VISTA Science Experience Center · Curators: Stephanie Kneissl, Florian Semlitsch, Theresa Steiner · Exhibition Design: Nofrontiere Design GmbH · Design: Lucy Li, Leo Mühlfeld · Code: Alan Schiegl, · Technical Assistance: Alexander Hackl · Thanks to: Quentin Bolsée, Alan Han